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A product becomes not profitable when its COGS and its share of the expenses are higher than its revenue. You may still want to keep the product (it is called a lost leader) because its presence could attract customers to purchase more profitable products, but as a general rule you would want to "fix" this problem in one of the following ways:
Related Questions:
How do I choose prices?
How do I change the price for a product?
How can I lower COGS?
How do I change the number of units that I expect to sell?
What does it mean to cover your fixed costs?
How do I relate raw materials to products I sell?